Cancer progression
Introduction
Epigenetics and Cancer
Research Interest
The long term research goal of my laboratory is to decipher molecular mechanisms of two closely-related processes, 1) metastasis, i.e., the spread of cancer to distant organs and 2) self-seeding, i.e., the return of circulating tumors cells to the origin of tumor.  Specifically, we are interested in epigenetic mechanisms that control the expression of genes used in afore-mentioned processes.

In order to investigate these processes, we are using various approaches including cell culture-based studies, mouse xenograft model of diseases as well as genome-wide screening.

Our goal is not only to dissect the molecular mechanisms of cancer progression but ultimately to translate the insights obtained in basic research into clinical treatment of cancers.
For Tumors, What Goes Around
         Comes Around

  Cell. Volume 139 (7) , 1315
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