SWISS-PROT is a curated protein
sequence database which strives to provide a high level of annotations (such as
the description of the function of a protein, its domains structure,
post-translational modifications, variants, etc.), a minimal level of redundancy
and high level of integration with other databases.
TrEMBL is a computer-annotated supplement of SWISS-PROT
that contains all the translations of EMBL nucleotide sequence entries not yet
integrated in SWISS-PROT.
PROSITE is a database of protein families and domains.
It consists of biologically significant sites, patterns and profiles that help
to reliably identify to which known protein family (if any) a new sequence
EcoCyc is a literature-derived electronic reference
source for E. coli biologists, and for biologists who work with related
microorganisms. The database contains up-to-date annotations of all E. coli
genes, as well as the DNA sequence of each E. coli gene. EcoCyc describes all
known pathways of E. coli small-molecule metabolism. Each pathway and its
component reactions and enzymes are annotated in rich detail, with extensive
references to the biomedical literature.
KEGG is an effort to computerize current knowledge of molecular and
cellular biology in terms of the information pathways that consist of
interacting molecules or genes and to provide links from the gene catalogs
produced by genome sequencing projects. The KEGG project is undertaken in the
Bioinformatics Center, Institute for Chemical Research, Kyoto University with
supports from the Ministry of Education, Culture, Sports, Science and Technology
and the Japan Society for the Promotion of Science.